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AGROSUS will identify appropriate tools and agroecological strategies to prevent and manage weeds in relevant crops, in conventional, organic, and mixed farming, in all the 11 biogeographic regions (Alpine, Anatolian, Arctic, Atlantic, Black Sea, Boreal, Continental, Macaronesian, Mediterranean, Pannonian and Steppic) of the EU and associated countries, with the aim to reduce reliance on synthetic herbicides and the correlated pressure on the environment. AGROSUS will co-develop the tools and strategies for the most problematic weeds of the different regions and crops in collaboration with stakeholders, and the short, medium, and long-term impact of the agroecological strategies will be analysed from environmental and socio-economic perspectives.